Faculty Practice · Mount Sinai Health System · Upper East Side, NYC
4.9 · 80 Google reviews  ·  U.S. News profile  ·  234 East 85th St, Manhattan · 212-241-9410
Alfred Iloreta, MD Director · Endoscopic Skull Base Surgery
Research · Recovery science

Recovery, treated as a science.

How much should sinus surgery hurt, and how few opioids can get you through it? The practice runs randomized controlled trials on the recovery experience itself — from gabapentin-based opioid-sparing protocols to virtual reality as analgesia during awake office procedures.

Why it matters

Evidence, not habit.

Much of perioperative care is inherited habit. The group's double-blind randomized trial of gabapentin for sinus surgery measured what actually reduces pain and opioid consumption after FESS. A companion RCT asked the optimal pre-operative corticosteroid dose in polyp disease — enough to shrink inflammation, no more than needed.

A third line of trials studies virtual reality as distraction analgesia during awake, office-based procedures — directly relevant to the practice's in-office hybrid OR program, where patient comfort without general anesthesia is the entire premise.

Key publications

Selected papers.

  • Gabapentin and postoperative pain and opioid consumption: A double-blind randomized controlled trial of perioperative pain management for sinus surgery. American Journal of Otolaryngology, 2023. PubMed · DOI
  • Seeking an optimal dose of preoperative corticosteroids in chronic rhinosinusitis with nasal polyposis: A randomized controlled trial. American Journal of Otolaryngology, 2022. PubMed
  • Virtual Reality as Distraction Analgesia for Office-Based Procedures: A Randomized Crossover-Controlled Trial. Otolaryngology–Head and Neck Surgery, 2020. PubMed
  • Factors Associated with High-Risk Ergonomic Postures During Office-based Rhinology Procedures: A Pilot Biomechanical Analyses. International Forum of Allergy & Rhinology, 2025. PubMed

Questions about this research — or a case it could help? Reach out.

Request a consultation →
← All publications